研究兴趣涉及生物医用高分子材料、光子晶体与结构色材料、细胞培养、组织工程、3D打印、科普宣教等领域,研究方向如下:
1)新型水凝胶材料的设计与应用
2)功能化层层自组装膜的设计与应用
招生方向:高分子化学与物理
欢迎有好奇心、探索心和执行力的同学来课题组开展有意义又有趣的科研工作。
1988年-1992年,陕西师范大学化学系本科
1992年-1996年,新疆医科大学基础部化学教研室助教
1996年-2001年,中国科学院成都有机化学研究所博士生
2001年-2003年,德国Max Planck Institute of Colloids and Interfaces博士后
2006年-2022年,新葡的京集团3512vip高分子化学研究所副教授
2023年-至今,新葡的京集团3512vip高分子化学研究所教授
截止2021年8月,作为项目负责人主持国家自然科学基金面上项目4项,在研2项;天津市面上项目1项,已结题。已在Angew. Chem., Chem. Soc. Rev., Science China Chemistry, Macromolecules, Biomarcromolecules等期刊发表学术论文120篇,H-index 36;获得3项中国专利;撰写专著章节一章。
代表性文章分类如下:
综述:
1. Guan Y, Zhang YJ. Progress in the Study of Microgel Colloidal Crystals. ACTA POLYMERICA SINICA. 2017(11): 1739-1752.
2. Guan Y, and Zhang YJ. Boronic acid-containing hydrogels: synthesis and their applications. CHEMICAL SOCIETY REVIEWS, 2013. 42(20): 8106-8121.
3. Guan Y, and Zhang YJ. PNIPAM microgels for biomedical applications: from dispersed particles to 3D assemblies. SOFT MATTER, 2011. 7(14): 6375-6384.
4. 关英,张拥军等. 层层自组装膜的研究: 从基础到生物医学领域中的应用. 高分子通报, 2013(1): 第40-52页
延迟释放药物载体设计:
1. Wang H., et al. A highly programmable platform for sequential release of protein therapeutics. JOURNAL OF MATERIALS CHEMISTRY B. 2021, 9(6): 1616-1624
2. Zhao Y., et al. Dynamic Layer-by-Layer Films: A Platform for Zero-Order Release. BIOMACROMOLECULES, 2015. 16(7): 2032-2039
氧化还原性水凝胶设计:
1. Hou J., et al. Enzymatically crosslinked alginate hydrogels with improved adhesion properties. POLYMER CHEMISTRY, 2015. 6(12): 2204-2213.
2. Zhang A., et al. Oxidative polymerization of hydroquinone using deoxycholic acid supramolecular template. SCIENCE CHINA-CHEMISTRY. 2012, 55(5SI): 830-835.
3. He J., et al. Novel Redox Hydrogel by in Situ Gelation of Chitosan as a Result of Template Oxidative Polymerization of Hydroquinone. MACROMOLECULES, 2011. 44(7): 2245-2252.
光子晶体制备及应用:
1. Yao L., et al. Tetrahedral, Octahedral, and Triangular Dipyramidal Microgel Clusters with Thermosensitivity Fabricated from Binary Colloidal Crystals Template and Thiol-Ene Reaction[J]. ACS MACRO LETTERS. 2018, 7(1): 80-84.
2. Liu Y., et al. New polymerized crystalline colloidal array for glucose sensing. CHEMICAL COMMUNICATIONS, 2009(14): 1867-1869.
功能化层层自组装膜设计及应用:
1. Wang R., et al. A CO2-responsive hydrogel film for optical sensing of dissolved CO2. SOFT MATTER. 2019, 15(30): 6107-6115.
2. Li Q., et al. Thin hydrogel films based on lectin-saccharide biospecific interaction for label-free optical glucose sensing. SENSORS AND ACTUATORS B-CHEMICAL. 2018, 272: 243-251.
3. Song J., et al. Growth of giant silver dendrites on layer-by-layer assembled films. POLYMER, 2015. 63: 237–243.
3D多细胞球培养:.
1. Gu J, et al. Effect of particle size in a colloidal hydrogel scaffold for 3D cell culture. COLLOIDS AND SURFACES B-BIOINTERFACES. 2015, 136: 1139-1147.
2. Zhao Z, et al. Hydrogel Thin Film with Swelling-Induced Wrinkling Patterns for High-Throughput Generation of Multicellular Spheroids. BIOMACROMOLECULES. 2014, 15(9): 3306-3312.
授权专利:
1. 氧化还原活性聚对苯二酚微球及其制备方法,ZL201110003153.8
2. 一种持续恒速释放药物的药物载体,ZL201610115967.3
3. 多肽交联的蛋白质分子印迹聚合物及其制备方法和应用,ZL201910147938.9
联合培养硕士生18人